Antimicrobial Resistance and Sensitivity among Isolates of Esherichia coli from Urine Samples in Denizli, Turkey

Authors

  • Selma Kirac Pamukkale University
  • Dilek Keskin Adnan Menderes University
  • F. Banu Karahasanoğlu ER-PA Special Health Hospital

DOI:

https://doi.org/10.18034/mjmbr.v5i1.443

Keywords:

Escherichia coli, Antibiotic, Resistance, Prevalence, MDR

Abstract

Objective: The research was carried out with isolate and determines the antimicrobial sensitivity in E. coli from urinary tract infections in special hospital in Denizli and recorded at specimens.

Methods: Urine samples (n=21) were collected from patients with signs and symptoms of Urinary tract infections. Bacteria were isolated and identified by conventional biochemical profile. Antibiotic resistance pattern of E. coli against different antibiotic was determined by Kirby-Baur method.

Results: The results revealed that sensitivity rate of antimicrobial agents were in the range of meropenem (100%), norfloxacin and ciprofloxacin (86%), cefotaxime (80%), aztreonam (76%). None of the samples showed no resistance to amikacin, ceftazidime, aztreonam, amoxicillin/clavulanic acid, and meropenem. Out of 21 isolates, 3(14%) isolates showed Multiple Antibiotic Resistance ten to thirteen antibiotics.

Conclusion: It is concluded that most of the urinary tract infections in human are caused by E.coli exhibited highest resistance to meropenem (100%), followed by norfloxacin and ciprofloxacin  (86%).

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Author Biographies

  • Selma Kirac, Pamukkale University

    Denizli Health Services Vocational High School, Pamukkale University, Denizli, TURKEY

  • Dilek Keskin, Adnan Menderes University

    Cine Vocational High School, Adnan Menderes University, 09500- Cine-Aydin, TURKEY

  • F. Banu Karahasanoğlu, ER-PA Special Health Hospital

    ER-PA Special Health Hospital, Denizli, TURKEY

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2018-06-30

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Kirac, S. ., Keskin, D. ., & Karahasanoğlu, F. B. . (2018). Antimicrobial Resistance and Sensitivity among Isolates of Esherichia coli from Urine Samples in Denizli, Turkey . Malaysian Journal of Medical and Biological Research, 5(1), 13-18. https://doi.org/10.18034/mjmbr.v5i1.443