Antimicrobial Study of Oil and Stem Bark Extracts of Pentaclethra Macrophylla Benth on Six Selected Pathogens


  • A. M. Yusuf Babatunde Ogun State College of Health Technology
  • L. S. Kasim Olabisi Onabanjo University
  • Adegbite A. Ayoade Ogun State College of Health Technology



Pentaclethra macrophylla benth, antimicrobial, clinical isolates


The antimicrobial activity of oil and stem bark extracts of pentaclethra macrophylla benth was determined against staphylococcus aureus, streptococcus pneumonia, Eschericia coli, Haemophilus influenza, α-Haemolytic Streptococcus and Yeast, using hole diffusion method. The results revealed that the most inhibitory zone (25.0mm) was recorded in hexane oil extract against staphylococcus aureus and α-Haemolytic Streptococcus. The minimum inhibitory concentration (MIC) of the oil extract ranges between 7.8125-62.5mg/ml on all the test organisms and aqueous stem bark extract inhibited only Eschericia coli with minimum, inhibitory concentration (MIC) of 62.5mg/ml. However, the oil extract possessed more antimicrobial activity than the stem bark extract. These findings lend more knowledge to the use of pentaclethra macrophylla benth for medicinal purposes.



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Author Biographies

  • A. M. Yusuf Babatunde, Ogun State College of Health Technology

    Department of Pharmaceutical Technology, Ogun State College of Health Technology, Ilese-Ijebu, NIGERIA

  • L. S. Kasim, Olabisi Onabanjo University

    Department of Pharmaceutical and Medicinal Chemistry, Faculty of Pharmacy, Olabisi Onabanjo University, Sagamu Campus, Ogun State, NIGERIA

  • Adegbite A. Ayoade, Ogun State College of Health Technology

    Department of Water Resources Management and Sanitation, Ogun State College of Health Technology, Ilese-Ijebu, NIGERIA


Akah, P.A., Aguwa, C.N., and Agu, R.U. (1999). Studies on the andiarrhoeal properties of Pentaclathramacrophylla leaf extracts. African Journal of Traditional complementary and Alternative Mediumes, Vol. 3, 44-53.

Cousin D. and Huffman, M.A (2002). Medicinal Properties in thte Diet of Gorrilas, and Ethnopharmacological Evaluation. African studies Monographs, 23 (2); 65-89.

Ibekwe, V.I., Ugbochi, K.C and Anyanwu, B.N. (2002). The prevalence of Penicillin Resistant in Organisms that cause sexually transmitted disease in Port-Harcourt Nigeria. Int. J. Environmental Health Res:10:251-255.

Kamanzi, Aundehou, K., Kone, M., terreaux, C., Traore, D., Hostettman, K, and Dosso, M. (2002). Evaluation of the Antimicrobial potential of Medicinal Plants from Ivory Coast. Phytother Res:497-502.

Ladipo, d.O., Kang, B.T., and Swift, M.J. (1993). Nodulation in PentaclethramacrophyllaBenth; A multi-purpose tree with potential for agroforestry in the humid lowlands of West Africa, Nitrogen Fixing Tree Reports 11:104-105.

Montefioure, D., Rotimi, V.O., and Deyemi-Doro F.A.B. (1989). The problem of bacteria Resistance to Anti-biotic among strains isolated from Hospital Patients in Lagos and Ibadan, Nigeria. J.Antimicrobial Chemotherapy.23:641-651.

Oboh, G., (2007) Pentaclethra macrophylla Benth. In: van der Vossen, H.A.M. & Mkamilo, G.S. (Editors). PROTA 14: Vegetable oils/Oléagineux. [CD-Rom]. PROTA, Wageningen, Netherlands.

Odoemelain, S.A., (2005). Proxinatecompostition and selected physiochemical properties of the seeds of Oil Bean. Pakistan J. Nutri 4(6) 382-383.

Okorie, C.C., oparaocha, E.N.T., Adewunmi, O., Iwalewa, E.o., and Omodara, S.K. (2006). African Journal of Traditional, Complementary and Alternative medicine Vol. 3 pp44-53.

Olaitan, J.o., Kareem S.O., and Dada, S.O., (2009). Antimicrobial Potency of Pentaclethra Macrophyll seed Extract on seven selected pathogens. African Journal of Biomedical Research Vol. 12 No. 2 Pp 141-144.

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Peer-reviewed Article

How to Cite

Babatunde, A. M. Y. ., Kasim, L. S. ., & Ayoade, A. A. . (2016). Antimicrobial Study of Oil and Stem Bark Extracts of Pentaclethra Macrophylla Benth on Six Selected Pathogens. Malaysian Journal of Medical and Biological Research, 3(1), 7-10.

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